| 姓名 |
江正强 |
|
| 性别 |
男 |
| 出生日期 |
1971年6月10 |
| 籍贯 |
河南 |
| 民族 |
汉 |
| 学历/学位 |
|
| 职称 |
教授 教育部人才项目特聘教授；国家杰出青年基金获得者 |
联系方式
电话： 86-10-62737689；
传真： 86-10-82388508；
E-mail： zhqjiang@cau.edu.cn
实验室网站 http://foodenzyme.cau.edu.cn
通信地址：北京市海淀区清华东路17号中国农业大学（东区）294信箱 邮 编：100083
学习工作经历
1995年留校工作。
1998 年9月～1999年3月在日本神户大学农学部进修。
2000 年3月～2001年3月作为联合国大学研究员在日本食品综合研究所酶工程研究室进行合作研究。
2001年9月晋升为副教授。
2004年12月晋升为教授。
2005年9月～2006年7月在法国食品工业大学（南特）进行合作研究。
2013年8月～10月在德国吕贝克大学进行合作研究
现任职务（社会兼职等）
中国生物发酵产业协会，理事；中国食品科学技术学会酶制剂分会，常务理事；中国粮油学会发酵面食分会，常务理事；中国农业工程学会农产品加工分会，常务理事；北京市食品学会，理事；美国微生物学会，会员。
《中国粮油学报》和《中国酿造》编委等。
主要研究方向
1）食品酶与发酵工程：新型食品酶基因的克隆和表达、酶制剂的发酵生产、纯化、性质和应用；新酶的结构解析及分子改造：如新型葡聚糖酶、酯酶、几丁质酶等；
2）食品科学与工程方向：低聚糖的生产和功能、传统发酵食品和粮油加工食品等。
3）其他：新资源食品、食用有机酸发酵及生物质资源高效利用等；
代表著作、论文与专利
著有专业著作4部，代表性专著《酶与酶工程及其应用》（副主编，主笔16万字，2006年7月化学工业出版社出版）和《焙烤食品工艺学(第2版)》（副主编，主笔25万字，2010年1月中国轻工业出版社出版）。
在国内外刊物发表学术论文200余篇，其中SCI收录论文80多篇论文被引用1000多次，全部SCI论文的h index为22。授权国家发明专利30多项。
代表性SCI收录论文
1.Yu Guo; Qiaojuan Yan; Yu Yang; Shaoqing Yang; Yu Liu; Zhengqiang Jiang*. Expression and characterization of a novel β-glucosidase with transglycosylation and exo-β-1,3-glucanase activities from Rhizomucor miehei. Food Chemistry, 2015, 175: 431–438.
2.Yang, Shaoqing; Xiong, Hao; Yang, Hongye; Yan, Q.J.; Jiang, Zhengqiang*.High-level production of β-1,3-1,4-glucanase by Rhizomucor miehei under solid-state fermentation and its potential application in the brewing industry. Journal of Applied Microbiology, 2015, 118(1): 84-91.
3.Zhou Chen, Yu Liu, Qiaojuan Yan*, Shaoqing Yang, Zhengqiang Jiang*. Biochemical Characterization of a Novel Endo-1,5-α-L-arabinanase from Rhizomucor miehei. Journal of Agricultural and Food Chemistry, 2015, 63 (4): 1226-1233.
4.Qiao-Juan Yan*, Lin-Hua Huang, Qian Sun, Zheng-Qiang Jiang*, Xia Wu. Isolation, identification and synthesis of four novel antioxidant peptides from rice residue protein hydrolyzed by multiple proteases. Food Chemistry 2015, 179: 290-295.
5.Zhou Chen; Qiaojuan Yan*; Yu Liu; zhqjiang Jiang*; Yuchen Liu. High-level expression of a novel α-galactosidase gene from Rhizomucor miehei in Pichia pastoris and characterization of the recombinant enzyme. Protein Expression and Purification, 2015, 110: 107-114.
6.Xing Fu, Qiaojuan Yan,Shaoqing Yang, Xinbin Yang, Yu Guo, and Zhengqiang Jiang*.An acidic, thermostable exochitinase with β-N-acetylglucosaminidase activity from Paenibacillus barengoltzii converting chitin to N-acetyl glucosamine. Biotechnology for Biofuels 2014, 7:174.
7.Xiaojie Duan, Songqing Hu, Peng Zhou, Yong Zhou, Yu Liu, Zhengqiang Jiang∗.Characterization and crystal structure of a first fungal glyoxylate reductase from Paecilomyes thermophila. Enzyme and Microbial Technology 2014, 60: 72–79.
8.Peng Zhou, Guoqiang Zhang, Shangwu Chen, Zhengqiang Jiang*, Yanbin Tang, Bernard Henrissat,Qiaojuan Yan, Shaoqing Yang, Chin-Fu Chen, Bing Zhang* and Zhenglin Du. Genome sequence and transcriptome analyses of the thermophilic zygomycete fungus Rhizomucor miehei. BMC Genomics 2014, 15:294.
9.Shupeng Wu, Yu Liu, Qiaojuan Yan, Zhengqiang Jiang*.Gene cloning, functional expression and characterisation of a novelglycogen branching enzyme from Rhizomucor miehei and its applicationin wheat breadmaking. Food Chemistry 2014, 159:85-94.
10.Linhua Huang, Yu Liu, Yan Sun, Qiaojuan Yan* and Zhengqiang Jiang*. Biochemical characterization of a novel L-Asparaginase with low glutaminase activity from Rhizomucor miehei and its application in food safety and leukemia treatment. Appl. Environ. Microbiol. 2014, 80(5):1561-1569.
11.Katrolia, Priti，Rajashekhara, Eranna，Yan, Qiaojuan，Jiang, Zhengqiang(*)，Biotechnological potential of microbial alpha-galactosidases. Critical Reviews in Biotechnology，2014，34（4）：307-317.
12.Zhou, Peng，Liu, Yang，Yan, Qiaojuan，Chen, Zhongzhou，Qin, Zhen，Jiang, Zhengqiang(*)，Structural insights into the substrate specificity and transglycosylation activity of a fungal glycoside hydrolase family 5 beta-mannosidase. Acta Crystallographica Section D-Biological Crystallography，2014，70：2970-2982.
13.Yan, Qiao-juan，Yang, Shao-qing，Duan, Xiao-jie，Xu, Hai-bo，Liu, Yu，Jiang, Zheng-qiang(*)，Characterization of a novel hormone-sensitive lipase family esterase from Rhizomucor miehei with tertiary alcohol hydrolysis activity. Journal of Molecular Catalysis B: Enzymatic，2014，109：76-84.
14.Yang, Shaoqing，Xiong, Hao，Yan, Qiaojuan，Yang, Hongye，Jiang, Zhengqiang(*)，Purification and characterization of a novel alkaline beta-1,3-1,4-glucanase (lichenase) from thermophilic fungus Malbranchea cinnamomea. Journal of Industrial Microbiology and Biotechnology，2014，41（10）：1487-1495.
15.Fan, Guangsen，Yang, Shaoqing，Yan, Qiaojuan，Guo, Yu，Li, Yanxiao，Jiang, Zhengqiang(*)，Characterizati on of a highly thermostable glycoside hydrolase family 10 xylanase from Malbranchea cinnamomea. International Journal of Biological Macromolecules，2014，70：482-489.
16.Sun, Qian，Wang, Xi-Ping，Yan, Qiao-Juan，Chen, Wei，Jiang, Zheng-Qiang(*)，Purification and Characterization of a Chymosin from Rhizopus microsporus var. rhizopodiformis. Applied Biochemistry and Biotechnology，2014，174（1）：174-185.
17.Yang, Shaoqing，Song, Shuang，Yan, Qiaojuan，Fu, Xing，Jiang, Zhengqiang(*)，Yang, Xinbin，Biochemical characterization of the first fungal glycoside hydrolyase family 3 beta-N-Acetylglucosaminidase from Rhizomucor miehei. Journal of Agricultural and Food Chemistry，2014，62（22）：5181-5190.
18.Peng Zhou, Zhongzhou Chen, Qiaojuan Yan, Shaoqing Yang, Rolf Hilgenfeld, Zhengqiang Jiang*. The structure of a glycoside hydrolase family 81 endo-β-1,3-glucanase. Acta Crystallographica Section D-Biological Crystallography, 2013, D69, 2027–2038.
19.Shaoqing Yang, Chengwei Hua, Qiaojuan Yan, Yinan Li, Zhengqiang Jiang*. Biochemical properties of a novel glycoside hydrolase family 1 β-glucosidase gene (PtBglu1) from Paecilomyces thermophila expressed in Pichia pastoris. Carbohydrate Polymers, 2013, 92(1):784–791.
20.Jianzhi Zhang, Narasimha Kumar Kopparapu, Qiaojuan Yan, Shaoqing Yang, Zhengqiang Jiang*. Purification and characterization of a novel chitinase from persimmon (Diospyros kaki) with antifungal activity. Food Chemistry, 2013, 138(2-3), 1225-1232.
21.Shaoqing Yang, Haibo Xu, Qiaojuan Yan, Yu Liu, Peng Zhou Zhengqiang Jiang*. A low molecular mass cutinase of Thielavia terrestris efficiently hydrolyzes Poly(esters). Journal of Industrial Microbiology & Biotechnology, 2013, 40 (2):217-226.
22.Priti Katrolia, Qiaojuan Yan, Pan Zhang, Peng Zhou, Shaoqing Yang, Zhengqiang Jiang*. Gene cloning and enzymatic characterization of an alkali-tolerant endo-1,4-β-mannanase from Rhizomucor miehei. Journal of Agricultural and Food Chemistry, 2013, 61(2):394-401.
23.Peng Han, Peng Zhou, Songqing Hu, Shaoqing Yang, Qiaojuan Yan, Zhengqiang Jiang*. A novel multifunctional α-amylase from the thermophilic fungus Malbranchea cinnamomea: Biochemical characterization and three-dimensional structure. Applied Biochemistry and Biotechnology, 170:420-435.
24.Priti Katrolia, Peng Zhou, Pan Zhang, Qiaojuan Yan, Yinan Li, Zhengqiang Jiang*, Haibo Xu. High level expression of a novel β-mannanase from Chaetomium sp. exhibiting efficient mannan hydrolysis. Carbohydrate Polymers, 2012, 87(1):480-490.
25.Narasimha Kumar Kopparapu, Shuping Zhang, Peng Zhou, Qiaojuan Yan, Zhengqiang Jiang*, Zhuqing Liu. Purification and characterization of a novel chitinase gene from Paecilomyces thermophila expressed in Escherichia coli. Carbohydrate Research, 2012, 347 (1): 155–160.
26.Qiaojuan Yan, Luo Tang, Shaoqing Yang, Shuping Zhang, Zhengqiang Jiang*. Purification and characterization of a novel thermostable α-L-arabinofuranosidase (α-L-AFase) from Chaetomium sp. Process Biochemistry, 2012, 47 (3): 472-478.
27.Linhua Huang, Qiaojuan Yan, Narasimha Kumar Kopparapu, Zhengqiang Jiang*, Yan Sun. Astragalus membranaceus lectin (AML) induces caspase-dependent apoptosis in human leukemia cells. Cell Proliferation, 2012, 45(1):15-21.
28.Yanbin Tang, Shaoqing Yang, Qiaojuan Yan, Peng Zhou, Jian Cui, Zhengqiang Jiang*. Purification and characterization of a novel β-1,3-1,4-glucanase (lichenase) from the thermophilic Rhizomucor miehei with high specific activity and its gene sequence. Journal of Agricultural and Food Chemistry, 2012, 60 (9), pp 2354–2361.
29.Priti Katrolia, Huiyong Jia, Qiaojuan Yan, Shuang Song, Zhengqiang Jiang*, Haibo Xu. Characterization of a protease-resistant α-galactosidase from the thermophilic fungus Rhizomucor miehei and its application in removal of raffinose family oligosaccharides. Bioresource Technology, 2012, 110:578-586.
30.Huiyong Jia, Guangsen Fan, Qiaojuan Yan, Yuchun Liu, Ye Yan, Zhengqiang Jiang*. High-level expression of a hyperthermostable Thermotoga maritima xylanase in Pichia pastoris by codon optimization. Journal of Molecular Catalysis B: Enzymatic, 2012, 78:72-77.
31.Huiyong Jia, Yinan Li, Yuchun Liu, Qiaojuan Yan, Shaoqing Yang, Zhengqiang Jiang*. Engineering a thermostable β-1,3-1,4-glucanase from Paecilomyces thermophila to improve catalytic efficiency at acidic pH. Journal of Biotechnology 2012, 159 (1-2):50-55.
32.Yan Qiaojuan, Chengwei Hua, Shaoqing Yang, Yinan Li, Zhengqiang Jiang*. High level expression of extracellular secretion of a β-glucosidase gene (PtBglu3) from Paecilomyces thermophila in Pichia pastoris. Protein Expression and Purification, 2012, 84:64-72.
33.Guangsen Fan, Huiyong Jia, Katrolia Priti, Shaoqing Yang, Qiaojuan Yan, Zhengqiang Jiang*. High-level expression of a xylanase gene from the thermophilic fungus Paecilomyces thermophila in Pichia pastoris. Biotechnology Letters, 2012, 34 (11):2043-2048.
34.Zhou Chen, Huiyong Jia, Yu Yang, Qiaojuan Yan, Zhengqiang Jiang* and Chao Teng. Secretory expression of a β-xylosidase gene from Thermomyces lanuginosus in Escherichia coli and characterization of its recombinant enzyme. Letters in Applied Microbiology, 2012, 55(5):330–337.
35.Teng C, Jia HY, Yan QJ, Zhou P, Zhengqiang Jiang*. High-level expression of extracellular secretion of a β-xylosidase gene from Paecilomyces thermophila in Escherichia coli. Bioresource Technology, 2011, 102(2):1822-1830.
36.Kopparapu NK, Liu ZQ, Yan QJ, Zhengqiang Jiang*, Zhang SP. A novel thermostable chitinase (PJC) from pomegranate (Punica granatum) juice. Food Chemistry, 2011, 127(4):1569-1575.
37.Zhou P, Zhu HF, Yan QJ, Katrolia P, Zhengqiang Jiang*. Purification and properties of a Psychrotrophic Trichoderma sp. xylanase and its gene sequence. Applied Biochemistry and Biotechnology, 2011, 164(6):944-956.
38.Kopparapu NK, Liu ZQ, Fei F, Yan QJ, Zhengqiang Jiang*. Purification and characterization of a chitinase (sAMC) with antifungal activity from seeds of Astragalus membranaceus. Process Biochemistry, 2011, 46(6): 1370-1374.
39.Katrolia P, Yan QJ, Jia HY, Li YN, Zhengqiang Jiang*, Song CL. Molecular cloning and high-level expression of a β-galactosidase gene from Paecilomyces aerugineus in Pichia pastoris. Journal of Molecular Catalysis B-Enzymatic, 2011, 69(3-4):112-119.
40.Katrolia P, Zhang M, Yan QJ, Zhengqiang Jiang*, Song CL, Li LT. Characterisation of a thermostable family 42 β-galactosidase (BgalC) family from Thermotoga maritima showing efficient lactose hydrolysis. Food Chemistry, 2011, 125(2):614-621.
授权发明专利30余项，代表性10项如下：
1. 江正强, 贾会勇, 闫巧娟, 李一男, 陈洲. 获得定向突变基因的方法和基于其发现的酸性β-1,3-1,4-葡聚糖酶[P]. 北京：CN103045560A, 2013-04-17.
2. 江正强, 贾会勇, 闫巧娟, 波利特, 宋爽. 一种α-半乳糖苷酶及其编码基因和应用[P]. 北京：CN103045562A, 2013-04-17.
3. 江正强, 华承伟, 杨绍青, 闫巧娟, 李一男. 一种β-葡萄糖苷酶及其编码基因与应用[P]. 北京：CN102477417A, 2012-05-30.
4. 江正强, 张敏, 波丽特, 宋春雷, 李里特. 一种耐高温β-半乳糖苷酶及其编码基因与应用[P]. 北京：CN101993864A, 2011-03-30.
5. 江正强, 杜雪丹, 闫巧娟, 唐艳斌. 一种制备β-葡聚糖酶的方法及其专用菌株[P]. 北京：CN101845423A, 2010-09-29.
6. 江正强, 贾会勇, 滕超, 周鹏, 闫巧娟. β-木糖苷酶及其编码基因与应用[P]. 北京：CN101724615A, 2010-06-09.
7. 江正强, 杨绍青, 闫巧娟, 王岚. 制备耐热木聚糖酶、耐热β-木糖苷酶或耐热β-葡萄糖苷酶的方法[P]. 北京：CN101012457, 2007-08-08.
8. 江正强, 李里特, 李道义, 朱运平. 一种生产木二糖的方法及其专用固定化酶[P]. 北京：CN1916171, 2007-02-21.
9. 江正强, 武爱民, 闫巧娟, 韦赟, 丛倩千. 一种生产甘露聚糖酶的方法及其专用固定化生物膜[P]. 北京：CN101492667, 2009-07-29.
10. 江正强, 郭洋, 闫巧娟, 滕超. 一种利用玉米芯生产L-乳酸的方法及其专用米根霉[P]. 北京：CN101724663A, 2010-06-09.
主要科研项目
目前主持的在研项目包括国家杰出青年基金、“863”计划以及横向合作项目等多项课题。
教学工作
主讲课程包括本科生的《食品酶学与酶工程原理》、《食品原料学》和研究生的《酶和酶工程专题》等。
奖励及其他
2014年教育部人才项目特聘教授和2013年获得国家杰出青年基金；荣获光华工程科技奖1项、中国青年科技奖1项、国家科技发明二等奖1项、国家科技进步二等奖1项、省部级科技进步二等奖2项和国际学术奖2项；入选科技部中青年科技创新领军人才和教育部“新世纪优秀人才”，另外博士论文获“全国优秀百篇博士论文”。
